RESPIMAT is designed to get medication deep into the lungs

STIOLTO RESPIMAT delivers medication efficiently and effectively independent of inspiratory effort.1

RESPIMAT can help your patients with:

  • Lung deposition 
  • Coordination 
  • Inhalation effort 

As with all inhaled drugs, the actual amount of drug delivered to the lung may depend on patient factors, such as the coordination between the actuation of the inhaler and inspiration through the delivery system. The duration of inspiration should be at least as long as the spray duration (1.5 seconds).

Delivers medication independent
of inspiratory

Lung DepositionCoordination Inhalation Effort

Lung Deposition Coordination Inhalation Effort 

STIOLTO starts to work in 5 minutes, and lasts a full 24 hours, making it an option for most of your COPD patients, including any current SPIRIVA® RESPIMAT® (tiotropium bromide) Inhalation Spray patients not meeting key treatment goals when lung function (FEV1) and health-related quality of life matter most.

STIOLTO is NOT a rescue medication and does NOT replace fast-acting inhalers to treat acute symptoms.


Designed for improved drug delivery2

COPD: dose deposition patient profile*

RESPIMAT Inhaler Improved Delivery RESPIMAT Inhaler Improved Delivery

There is no correlation between deposition data and clinical efficacy. Active ingredients used in the studies are not commercially available in RESPIMAT. The specific physical-chemical characteristics of the drug may affect the lung deposition.

*Data were collected from COPD patients who were initially untrained, and later trained in the optimal use of both inhalers. The images above are sample scintigraphic pictures, taken from 1 trained study patient, comparing drug deposition profiles. The percentage of dose deposition is the mean of 12 COPD study patients. For trained patients, the mean dose deposition in the peripheral/central lung zones for RESPIMAT was about twice that for HFA-MDI. The test drug for RESPIMAT and the HFA-MDI was Berodual® (fenoterol hydrobromide 50 mcg/ipratropium bromide 20 mcg).

Scintigraphy images reprinted with permission from Int J COPD 2008;3(4):763-770. © 2008 Brand et al, publisher and licensee Dove Medical Press Ltd.

References: 1. STIOLTO RESPIMAT [prescribing information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2016. 2. Brand P, Hederer B, Austen G, Dewberry H, Meyer T. Higher lung deposition with Respimat Soft Mist Inhaler than HFA MDI in COPD patients with poor technique. Int J COPD. 2008;3(4):763–770.

RESPIMAT Delivers, COPD Patient


Patients take STIOLTO just once a day1

The convenient once-daily dose of STIOLTO consists of two (2) puffs every 24 hours.1

Instructions for Use


Start patients on STIOLTO with confidence

As with most inhalers, using STIOLTO RESPIMAT once a day can quickly become part of your patients’ daily routine. With each refill, the RESPIMAT inhaler does need to be prepared.1

Start Patients on STIOLTO

On-demand support

If your patients ever have questions, or if your health care team would like help in educating and onboarding appropriate patients, we have everything you need, including videos, materials, and a free phone line staffed by respiratory experts.

HCP Support


STIOLTO RESPIMAT On-demand Support

Reference: 1. STIOLTO RESPIMAT [prescribing information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2016.

RESPIMAT Delivers, COPD Patient